2/15/2024 0 Comments Antidote for valiumSigns and symptoms of methemoglobinemia may be delayed by several hours after treatment with sodium nitrite. Close medical supervision is necessary when medications that can cause methemoglobinemia are used together. Individuals may be more susceptible to developing methemoglobinemia during treatment with these medications if they are very young (especially neonates and infants) or have anemia, diseases of the heart or lungs, blood circulation disorders, shock, sepsis, and certain genetic predispositions such as NADH cytochrome-b5 reductase deficiency, glucose-6-phosphate dehydrogenase deficiency, and hemoglobin M. Using sodium nitrite together with amyl nitrite may increase the risk of methemoglobinemia, a condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood. Flumazenil injection.Applies to: Cyanide Antidote Kit (amyl nitrite/sodium nitrite/sodium thiosulfate) and Cyanide Antidote Kit (amyl nitrite/sodium nitrite/sodium thiosulfate) British Journal of Clinical Pharmacology. Benzodiazepine dependence and its treatment with low dose flumazenil. Flumazenil versus placebo or no intervention for people with cirrhosis and hepatic encephalopathy. Goh ET, Andersen ML, Morgan MY, Gluud LL. Significant and safe shortening of the recovery time after flumazenil-reversed midazolam sedation. Mathus-Vliegen EM, de Jong L, Kos-Foekema HA. Benzodiazepine pharmacology and central nervous system–mediated effects.
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